川口 敦史 / Kawaguchi, Atsushi

医学医療系 教授 / Professor, Faculty of Medicine

関連記事 / Related Articles in COTRE

新型コロナウイルスに感染するマウスの作製 治療薬開発のヒントや重症化リスクの原因解明へ | 川口 敦史 | 筑波大学「知」活用プログラム 成果インタビュー
新型コロナウイルスに感染するマウスの作製 治療薬開発のヒントや重症化リスクの原因解明へ | 川口 敦史
Molecular Virology | 川口 敦史 | 筑波大学研究者カタログ
新型コロナ研究支援 筑波大学「知」活用プログラムウェブサイトを公開
ヒトと同じように新型コロナウイルスに感染し、 ウイルス性肺炎を起こすマウスを作り、治療薬開発の道を拓く Paving the way for the development of therapeutic drugs by creating mice that model COVID-19 infection and complicating viral pneumonia in humans
第4回TIAかけはし 成果報告会
気道上皮組織でインフルエンザウイルスを感知する病原体センサーのタンパク質を発見
感染とはどういう現象なのか 分子レベルで解明する
感染生物学リサーチユニット
Elucidate the phenomena of infection at the molecular level
Critical role of an antiviral stress granule containing RIG-I and PKR in viral detection and innate immunity
The structural basis for an essential subunit interaction in influenza virus RNA polymerase
Long Noncoding RNA NEAT1-Dependent SFPQ Relocation from Promoter Region to Paraspeckle Mediates IL8 Expression upon Immune Stimuli
#009:人類の強敵インフルエンザウイルスをたたく

 

論文 / Publication

  1. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes. SangJoon Lee, Akari Ishitsuka, Takahiro Kuroki, Yu-Hsien Lin, Akira Shibuya, Tsunaki Hongu, Yuji Funakoshi, Yasunori Kanaho, Kyosuke Nagata, Atsushi Kawaguchi 6 (16) (2021)
  2. 3CL Protease Inhibitors with an Electrophilic Arylketone Moiety as Anti-SARS-CoV-2 Agents. Sho Konno, Kiyotaka Kobayashi, Miki Senda, Yuta Funai, Yuta Seki, Ikumi Tamai, Laura Schäkel, Kyousuke Sakata, Thanigaimalai Pillaiyar, Akihiro Taguchi, Atsuhiko Taniguchi, Michael Gütschow, Christa E Müller, Koh Takeuchi, Mikako Hirohama, Atsushi Kawaguchi, Masaki Kojima, Toshiya Senda, Yoshiyuki Shirasaka, Wataru Kamitani, Yoshio Hayashi (2021)
  3. Potent mouse monoclonal antibodies that block SARS-CoV-2 infection Youjia Guo, Atsushi Kawaguchi, Masaru Takeshita, Takeshi Sekiya, Mikako Hirohama, Akio Yamashita, Haruhiko Siomi, Kensaku Murano 296 100346 - 100346 (2021)
  4. Interaction of influenza A virus NS2/NEP protein with the amino-terminal part of Nup214. Burçak Şenbaş Akyazi, Ayşegül Pirinçal, Atsushi Kawaguchi, Kyosuke Nagata, Kadir Turan 44 (2) 82 - 92 (2020)
  5. Influenza restriction factor MxA functions as inflammasome sensor in the respiratory epithelium Lee S, Ishitsuka A, Noguchi M, Hirohama M, Fujiyasu Y, Petric PP, Schwemmle M, Staeheli P, Nagata K, Kawaguchi A. Science Immunology 4 (40) eaau4643 (2019)
  6. Involvement of CTCF in transcription regulation of EGR1 at early G1 phase as an architecture factor Sekiya T, Kato K, Kawaguchi A, Nagata K Scientific Reports 9 (1) 329 (2019)
  7. Influenza A virus NS1 protein suppresses JNK1-dependent autophagosome formation mediated by Rab11a recycling endosomes Kuroki T, Osari S, Nagata K, Kawaguchi A Frontiers in Microbiology 9 3120 (2018)
  8. Stratifin regulates stabilization of receptor tyrosine kinases via interaction with ubiquitin-specific protease 8 in lung adenocarcinoma Yunjung Kim, Aya Shiba-Ishii, Tomoki Nakagawa, Shun-ichiro Iemura, Tohru Natsume, Noriyuki Nakano, Ryota Matsuoka, Shingo Sakashita, SangJoon Lee, Atsushi Kawaguchi, Yukio Sato, Masayuki Noguchi 1 - 16 (2018)
  9. Biochemical characterization of avian influenza viral polymerase containing PA or PB2 subunit from human influenza A virus Phu Tran Vinh Pham, Kadir Turan, Kyosuke Nagata, Atsushi Kawaguchi 20 (6) 353 - 359 (2018)
  10. Inhibition of influenza virus infection by Lentinus edodes mycelia extract through its direct action and immunopotentiating activity Takahiro Kuroki, Sangjoon Lee, Mikako Hirohama, Tomohiro Taku, Michiko Kumakura, Takahiro Haruyama, Kyosuke Nagata, Atsushi Kawaguchi 9 (MAY) 1164 (2018)
  11. Influenza A virus infection triggers pyroptosis and apoptosis of respiratory epithelial cells through type I IFN signaling pathway in a mutually exclusive manner Lee S, Hirohama M, Noguchi M, Nagata K, Kawaguchi A Journal of Virology 92 (14) (2018)
  12. Assembly and remodeling of viral DNA and RNA replicons regulated by cellular molecular chaperones Takeshi Sekiya, Yifan Hu, Kohsuke Kato, Mitsuru Okuwaki, Atsushi Kawaguchi, Kyosuke Nagata 10 (2) 445 - 452 (2018)
  13. Analysis by metadynamics simulation of binding pathway of influenza virus M2 channel blockers Yuri Sakai, Atsushi Kawaguchi, Kyosuke Nagata, Takatsugu Hirokawa 62 (1) 34 - 43 (2018)
  14. Cellular splicing factor UAP56 stimulates trimeric NP formation for assembly of functional influenza viral ribonucleoprotein complexes Yifan Hu, Vishal Gor, Kazuya Morikawa, Kyosuke Nagata, Atsushi Kawaguchi 7 (1) 14053 (2017)
  15. RLR-mediated antiviral innate immunity requires oxidative phosphorylation activity Takuma Yoshizumi, Hiromi Imamura, Tomohiro Taku, Takahiro Kuroki, Atsushi Kawaguchi, Kaori Ishikawa, Kazuto Nakada, Takumi Koshiba 7 (1) 5379 (2017)
  16. Mitotic phosphorylation of CCCTC-binding factor (CTCF) reduces its DNA binding activity Takeshi Sekiya, Kensaku Murano, Kohsuke Kato, Atsushi Kawaguchi, Kyosuke Nagata 7 (3) 397 - 404 (2017)
  17. Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity M. Minakuchi, K. Sugiyama, Y. Kato, T. Naito, M. Okuwaki, A. Kawaguchi, K. Nagata 91 (3) (2017)
  18. インフルエンザウイルスと核内構造 黒木崇央, 川口, 敦史 生体の科学(医学書院) (2017)
  19. Polycomb repressive complex 2 facilitates the nuclear export of the influenza viral genome through the interaction with M1 Masamitsu N. Asaka, Atsushi Kawaguchi, Yuri Sakai, Kotaro Mori, Kyosuke Nagata 6 33608 (2016)
  20. The RNA- and TRIM25-Binding Domains of Influenza Virus NS1 Protein Are Essential for Suppression of NLRP3 Inflammasome-Mediated Interleukin-1β Secretion. Moriyama M, Chen IY, Kawaguchi A, Koshiba T, Nagata K, Takeyama H, Hasegawa H, Ichinohe T Journal of Virology 90 (8) 4105 - 4114 (2016)

researchmap の論文リストを表示する Show the publication list on researchmap

※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。

論文のオープンアクセス版を読む Check out a freely downloadable version

知財 / Intellectual properties

  1. 特願1566428 : コロナウイルスの感染を予防又は治療するための医薬組成物 川口敦史, 丹治勇人
  2. 特願15664289 : 消毒組成物、洗浄組成物、防汚組成物、ウイルス不活性化組成物および非殺菌性組成物並びにバイオフィルムの除去および形成抑制用組成物 野村暢彦, ウタダアンドリューシンイチ, ダウインバクヴヤン, 川口敦史, リシャウジェ
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発行:筑波大学 URA研究戦略推進室・研究推進部