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ALUMNI

山本 直司 / Yamamoto, Naoshi 2024年4月現在、筑波大学が主たる所属機関ではありません

筑波大学 国際統合睡眠医科学研究機構 助教 / Assistant Professor, International Institute for Integrative Sleep Medicine, University of Tsukuba

 

論文 / Publication

  1. Essential structure of orexin 1 receptor antagonist YNT-707, Part IV: The role of D-ring in 4,5-epoxymorphinan on the orexin 1 receptor antagonistic activity Saitoh, T, Seki, K, Nakajima, R, Yamamoto, N, Kutsumura, N, Nagumo, Y, Irukayama-Tomobe, Y, Ogawa, Y, Ishikawa, Y, Tanimura, R, Yanagisawa, M, Nagase, H Bioorganic & Medicinal Chemistry Letters 29 2655 - 2658 (2019)
  2. Essential structure of orexin 1 receptor antagonist YNT-707, Part III: Role of the 14-hydroxy and the 3-methoxy groups in antagonistic activity toward the orexin 1 receptor in YNT-707 derivatives lacking the 4,5-epoxy ring Yamamoto, N, Ohrui, S, Okada, T, Saitoh, T, Kutsumura, N, Nagumo, Y, Irukayama-Tomobe, Y, Ogawa, Y, Ishikawa, Y, Watanabe, Y, Hayakawa, D, Gouda, H, Yanagisawa, M, Nagase, H Bioorganic & Medicinal Chemistry 27 1747 - 1758 (2019)
  3. A Novel Rearrangement Reaction of Morphinan to Arylmorphan Skeletons and the Pharmacologies of Arylmorphan Derivatives Yata, M, Kutsumura, N, Nagumo, Y, Yamamoto, N, Saitoh, T, Ishikawa, Y, Irukayama-Tomobe, Y, Yanagisawa, M, Nagase, H Heterocycles 99 134 - 144 (2019)
  4. Oxidative Cleavage of the Acyl-Carbon Bond in Phenylacetone with Electrogenerated Superoxide Anions Zhang, Y, Sugai, T, Yamamoto, T, Yamamoto, N, Kutsumura, N, Nishiyama, S, Einaga, Y, Saitoh, T, Nagase, H ChemElectroChem 6 4194 - 4198 (2019)
  5. Essential structure of orexin 1 receptor antagonist YNT-707, Part II: Drastic effect of the 14-hydroxy group on the orexin 1 receptor antagonistic activity Sayaka Ohrui, Naoshi Yamamoto, Tsuyoshi Saitoh, Noriki Kutsumura, Yasuyuki Nagumo, Yoko Irukayama-Tomobe, Yasuhiro Ogawa, Yukiko Ishikawa, Yurie Watanabe, Daichi Hayakawa, Hiroaki Gouda, Masashi Yanagisawa, Hiroshi Nagase 28 (4) 774 - 777 (2018)
  6. Favorskii-Type Rearrangement of the 4,5-Epoxymorphinan Skeleton Kutsumura, N, Koyama, Y, Suzuki, Y, Tominaga, K, Yamamoto, N, Saitoh, T, Nagumo, Y, Nagase, H Organic Letters 20 1559 - 1562 (2018)
  7. Synthesis of Novel 1,3-Dioxa-5-thiazatriquinane and 1-Oxa-3,5-dithiazatriquinane Derivatives and their Pharmacologies Ohshita, R, Kutsumura, N, Nagumo, Y, Yamamoto, N, Saitoh, T, Hirayama, S, Fujii, H, Nagase, H Heterocycles 97 687 - 695 (2018)
  8. Essential structure of orexin 1 receptor antagonist YNT-707, Part I: Role of the 4,5-epoxy ring for binding with orexin 1 receptor Naoshi Yamamoto, Sayaka Ohrui, Takahiro Okada, Masahiro Yata, Tsuyoshi Saitoh, Noriki Kutsumura, Yasuyuki Nagumo, Yoko Irukayama-Tomobe, Yasuhiro Ogawa, Yukiko Ishikawa, Yurie Watanabe, Daichi Hayakawa, Hiroaki Gouda, Masashi Yanagisawa, Hiroshi Nagase 27 (17) 4176 - 4179 (2017)
  9. The application of a specific morphinan template to the synthesis of galanthamine Naoshi Yamamoto, Takahiro Okada, Yukimasa Harada, Noriki Kutsumura, Satomi Imaide, Tsuyoshi Saitoh, Hideaki Fujii, Hiroshi Nagase 73 (39) 5751 - 5758 (2017)
  10. Antitrichomonal activity of δ opioid receptor antagonists, 7-benzylidenenaltrexone derivatives Kutsumura, N, Koyama, Y, Nagumo, Y, Nakajima, R, Miyata, Y, Yamamoto, N, Saitoh, T, Yoshida, N, Iwata, S, Nagase, H Bioorganic & Medicinal Chemistry 25 (16) 4375 - 4383 (2017)

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※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。

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