渋谷 彰 / Shibuya, Akira

医学医療系 教授 / Professor, Faculty of Medicine

関連記事 / Related Articles in COTRE

Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes
Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation
An immunoglobulin-like receptor, Allergin-1, inhibits immunoglobulin E-mediated immediate hypersensitivity reactions
Positional identification of an asthma susceptibility gene on human chromosome 5q33
The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors
Gut dysbiosis promotes M2 macrophage polarization and allergic airway inflammation via fungi-induced PGE2
免疫難治疾患を対象とした免疫受容体分子標的療法の開発
ダニによるアトピーを抑制 副作用少ない治療を目指す
ダニによるアトピー性皮膚炎を抑制する分子の発見
薬剤性急性肝障害を予防する新しい細胞の働きを発見
細胞が自らアレルギーの発症を抑える仕組みを発見
免疫細胞が敗血症の発症を促進する ~“常識”を覆す新発見(2016.05)
粘膜の死細胞が腸炎、アトピー性皮膚炎、喘息の発症を促進する(2016.02)
免疫の基本原理を明らかにするこ とで疾患を克服する
難治性免疫疾患・アレルギー発症の分子機構解析と分子標的治療開発リサーチユニット
Overcome diseases by revealing the basic principles of immunity
シグナル伝達の異常に起因した疾患 を治療する創薬開発に向けた研究
シグナル伝達と疾患リサーチユニット
Research for drug discovery to treat diseases caused by abnormal cellular signaling
CKD49!? -慢性腎臓病と49地区医師会との戦い
基礎・社会・臨床医学の連携による健康長寿の実現リサーチユニット
‘CKD49’- Approaches to Treat Patients with Chronic Kidney Disease in Cooperation with Medical Associations in 49 districts
NCRs and DNAM-1 mediate NK cell recognition and lysis of human and mouse melanoma cell lines in vitro and in vivo
Costimulatory Molecule DNAM-1 Is Essential for Optimal Differentiation of Memory Natural Killer Cells during Mouse Cytomegalovirus Infection
アレルギーを抑える「魔法」製薬会社と特効薬を開発中
腸内細菌のバランスの乱れが、喘息を悪化させるメカニズムを解明~新しい発想のアレルギー治療へ~
貪食細胞が細菌感染を感知する仕組みを解明

 

論文 / Publication

  1. ILC1: guardians of the oral mucosa against enemy viruses Nabekura, Tsukasa, Shibuya, Akira Immunity 54 (2) 196 - 198 (2021)
  2. Hemagglutinating virus of Japan-envelope containing programmed cell death-ligand 1 siRNA inhibits immunosuppressive activities and elicits antitumor immune responses in glioma Sugii, Narushi, Matsuda, Masahide, Okumura, Genki, Shibuya, Akira, Ishikawa, Eiichi, Kaneda, Yasufumi, Matsumura, Akira Cancer science 112 (1) 81 - 90 (2021)
  3. MAIR-II deficiency ameliorates cardiac remodelling post-myocardial infarction by suppressing TLR9-mediated macrophage activation Yonebayashi, Saori, Tajiri, Kazuko, Murakoshi, Nobuyuki, Xu, Dongzhu, Li, Siqi, Feng, Duo, Okabe, Yuta, Yuan, Zixun, Song, Zonghu, Aonuma, Kazuhiro, Shibuya, Akira, Aonuma, Kazutaka, Ieda, Masaki JOURNAL OF CELLULAR AND MOLECULAR MEDICINE 24 (24) 14481 - 14490 (2020)
  4. Tumor-derived soluble CD155 inhibits DNAM-1-mediated antitumor activity of natural killer cells. Okumura, Genki, Iguchi, Akiko, Murata, Rikito, Kanemaru, Yumi, Shibuya, Akira, Shibuya, Kazuko The Journal of Experimental Medicine 217 (4) (2020)
  5. A mathematical model for dynamics of soluble form of DNAM-1 as a biomarker for graft-versus-host disease Y, Goshima, S, Nakaoka, K, Ohashi, H, Sakamaki, Shubuya, kazuko, Shibuya, Akira PLOS ONE 15 (2) (2020)
  6. Type 1 innate lymphoid cells: Soldiers at the front line of immunity Nabekura, Tsukasa, Shibuya, Akira Biomedical Journal (2020)
  7. Type 1 Innate Lymphoid Cells Protect Mice from Acute Liver Injury via Interferon-γ Secretion for Upregulating Bcl-xL Expression in Hepatocytes Nabekura, Tsukasa, Riggan, Luke, Hildreth, Andrew D, O’Sullivan, Timothy E, Shibuya, Akira IMMUNITY 52 (1) 96 - 108 (2020)
  8. Allergin-1 Immunoreceptor Suppresses House Dust Mite-Induced Allergic Airway Inflammation Miki, Haruka, Tahara-Hanaoka, Satoko, Almeida, Mariana Silva, Hitomi, Kaori, Shibagaki, Shohei, Kanemaru, Kazumasa, Lin, Yu-Hsien, Iwata, Kanako, Miyake, Shota, Shibayama, Shiro, Sumida, Takayuki, Shibuya, Kazuko, Shibuya, Akira Journal of Immunology 204 (4) 753 - 762 (2020)
  9. Allergin-1 Immunoreceptor Suppresses House Dust Mite-Induced Allergic Airway Inflammation Miki, Haruka, Tahara-Hanaoka, Satoko, Almeida, Mariana Silva, Hitomi, Kaori, Shibagaki, Shohei, Kanemaru, Kazumasa, Lin, Yu-Hsien, Iwata, Kanako, Miyake, Shota, Shibayama, Shiro, Sumida, Takayuki, Shibuya, Kazuko, Shibuya, Akira Journal of immunology (Baltimore, Md. : 1950) (2020)
  10. Clec10a regulates mite-induced dermatitis. Kazumasa Kanemaru, Emiko Noguchi, Satoko Tahara-Hanaoka, Seiya Mizuno, Hiroaki Tateno, Kaori Denda-Nagai, Tatsuro Irimura, Hiroshi Matsuda, Fumihiro Sugiyama, Satoru Takahashi, Kazuko Shibuya, Akira Shibuya 4 (42) (2019)
  11. Cutting Edge: Involvement of the Immunoreceptor CD300c2 on Alveolar Macrophages in Bleomycin-Induced Lung Fibrosis Nakazawa, Yuta, Ohtsuka, Shigeo, Nakahashi-Oda, Chigusa, Shibuya, Akira Journal of immunology (Baltimore, Md. : 1950) 203 (12) 3107 - 3111 (2019)
  12. Expression and function of DNAM-1 on human B-lineage cells Nagayama-Hasegawa, Yuko, Honda, Shin-Ichiro, Shibuya, Akira, Shibuya, Kazuko Cytometry. Part B, Clinical cytometry Epub (2019)
  13. Selective expression of DNAM-1 (CD226) is required for small peritoneal macrophages to prime CD4(+) T cell Vo, A. V, Takenaka, E, Yamashita-Kanemaru, Y, Shibuya, A, Shibuya, K EUROPEAN JOURNAL OF IMMUNOLOGY 49 (3:SI) 493 - 493 (2019)
  14. Autonomous regulation of mast cell degranulation through an inhibitory receptor CD300a Wang, Y, Nakahashi-Oda, C, Shibuya, A EUROPEAN JOURNAL OF IMMUNOLOGY 49 (3:SI) 570 - 570 (2019)
  15. Intestinal Permeability and IgA Provoke Immune Vasculitis Linked to Cardiovascular Inflammation Noval, Rivas M, Wakita, D, Franklin, MK, Carvalho, TT, Abolhesn, A, Gomez, AC, Fishbein, MC, Chen, S, Lehman, TJ, Sato, K, 渋谷, 彰, Fasano, A, Kiyono, H, Abe, M, Tatsumoto, N, Yamashita, M, Crother, TR, Shimada, K, Arditi, M Immunity 51 (3) 508 - 521 (2019)
  16. High expression of soluble CD155 in estrogen receptor-negative breast cancer Iguchi, Akiko, Okumura, Genki, Ichioka, Emika, Kiyomatsu, Hiroko, Ikeda, Tatsuhiko, Bando, Hiroko, Shibuya, Akira, Shibuya, Kazuko Breast Cancer 27 (1) 92 - 99 (2019)
  17. Autonomous regulation of immunoglobulin E-mediated mast cell degranulation and immediate hypersensitivity reaction by an inhibitory receptor CD300a Y, Wang, C, Nakahashi-Oda, Y, Okayama, A, Shibuya JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY 144 (1) 323 (2019)
  18. 粘膜上皮細胞死による制御性T細胞数の制御 中澤優太, 小田, ちぐさ, 渋谷彰 医学のあゆみ 268 (13) 1140 - 1144 (2019)
  19. Identification and isolation of splenic tissue-resident macrophage sub-populations by flow cytometry. Satoshi Fujiyama, Chigusa Nakahashi-Oda, Fumie Abe, Yaqiu Wang, Kazuki Sato, Akira Shibuya 31 (1) 51 - 56 (2019)
  20. マスト細胞上のアラジン-1はヤケヒョウダニによるマウス気道過敏性を抑制する 柴垣 翔平, 田原 聡子, 渋谷 彰 臨床免疫・アレルギー科 71 (6) 583 - 589 (2019)

researchmap の論文リストを表示する Show the publication list on researchmap

※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。

論文のオープンアクセス版を読む Check out a freely downloadable version

知財 / Intellectual properties

  1. 13/204799 : 移植片対宿主病予知マーカーおよびその利用 渋谷 彰, 小島 寛
  2. 特願2008-509878 : 移植片対宿主病予知マーカーおよびその利用 渋谷,彰, 小島 寛
  3. 12/296345 : 移植片対宿主病予知マーカーおよびその利用 渋谷 彰, 小島 寛
  4. 07741115.5 : 移植片対宿主病予知マーカーおよびその利用 渋谷, 彰, 小島, 寛
  5. 特願2006-106951 : 移植片対宿主病予知マーカーおよびその利用 渋谷, 彰, 小島, 寛
筑波大学研究ポータル University of Tsukuba research information Portal
COTRE(コトリ)|COmmunity of Tsukuba REsearchers

発行:筑波大学 URA研究戦略推進室・研究推進部