長崎 幸夫 / Nagasaki, Yukio

数理物質系 教授 / Professor, Faculty of Pure and Applied Sciences

関連記事 / Related Articles in COTRE

Management of tumor growth and angiogenesis in triple-negative breast cancer by using redox nanoparticles
Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy
Non-isotope enriched phenylboronic acid-decorated dual-functional nano-assembles for an actively targeting BNCT drug
Encapsulation of tissue plasminogen activator in pH-sensitive self-assembled antioxidant nanoparticles for ischemic stroke treatment – Synergistic effect of thrombolysis and antioxidant –
Nitroxyl radical-containing nanoparticles for novel nanomedicine against oxidative stress injury
Smart siRNA delivery systems based on polymeric nanoassemblies and nanoparticles
A smart nanoprobe based on fluorescence-quenching PEGylated nanogels containing gold nanopartlcles for monitoring the response to cancer therapy
Stimuli-responsive smart nanogels for cancer diagnostics and therapy
An orally administered redox nanoparticle that accumulates in the colonic mucosa and reduces colitis in mice
脳梗塞に対する抗酸化ナノメディシン(RNP)の開発
抗がん剤副作用軽減へ薬開発 実用化目指す(2016.04)
がん細胞の代謝を利用して がんを見つけ出し、治療する
腫瘍特異的ヘムーポルフィリン代謝を利用した診断・治療法開発リサーチユニット
Detection and treatment of cancer using cancer cell metabolism
ナノ粒子・ナノ構造物で、副作用のない「理想のくすり」をつくりだす
筑波発ナノ粒子の包括的臨床応用リサーチユニット
Create “Ideal Drugs” without Adverse Effects Using Nanoparticles and Nanostructures
病気やケガで失われた神経機能の復活をめざして
生体機能制御・再生研究グループリサーチユニット
Recovering from Neurological Impairment due to Disease or Injury
脂質の量から質へ 生活習慣病治療のパラダイムシフトをめざして
脂質エネルギー代謝リサーチユニット
From Quantitative to Qualitative Aspects of Lipids: Toward a Paradigm Shift in the Treatment of Lifestyle-Related Diseases
世界一の粒子線治療研究拠点を目指す
次世代型粒子線がん治療の確立研究リサーチユニット
Development of a novel systemic gene delivery system for cancer therapy with a tumor-specific cleavable PEG-lipid

 

論文 / Publication

  1. A silica-based antioxidant nanoparticle for oral delivery of Camptothecin which reduces intestinal side effects while improving drug efficacy for colon cancer treatment Nguyen-Trinh, Quynh Nhu, Trinh, Kim Xuyen Thi, Trinh, Nhu-Thuy, Vo, Van Toi, Li, Nan, Nagasaki, Yukio, Vong, Long Binh Acta Biomaterialia (143) 459 - 470 (2022)
  2. Sorafenib-loaded Silica-containing Redox Nanoparticles for Oral Anti-liver fibrosis Therapy Tran, Hao Thi, Vong, Long Binh, Nishikawa, Yuji, Nagasaki, Yukio Journal of Controlled Release (345) 880 - 891 (2022)
  3. Design of poly(DOPA)-based nanoparticle for Parkinson's disease treatment with suppressing dyskinesia Nagasaki, Yukio, Sato, Yuna, Vong, Long, Chonpathompikunlert, Pennapa, Tanasawet, Supita, Hutamekalin, Pilaiwanwadee JOURNAL OF THE NEUROLOGICAL SCIENCES 429 (S) (2021)
  4. Self-Assembling Antioxidants for Ischemia-Reperfusion Injuries Yoshitomi, Toru, Nagasaki, Yukio ANTIOXIDANTS & REDOX SIGNALING Epub (2021)
  5. Design of Enzyme-responsive Short-Chain Fatty Acid-based Self-Assembling Drug for Alleviation of Type 2 Diabetes Mellitus Babita, Shashni, Yuya, Tajika, 長崎, 幸夫 Biomaterials 275 120877 (2021)
  6. Antioxidant nanomedicine significantly enhances the survival benefit of radiation cancer therapy by mitigating oxidative stress-induced side effects Ahram, KIM, Chiaki, Yonemoto, Chitho, P. Feliciano, Babita, Shashni, 長崎, 幸夫 Small 17 (21) e2008210 (2021)
  7. An Antioxidant Nanoparticle Enhances Exercise Performance in Rat High-intensity Running Models Toriumi, Takuto, Kim, Ahram, Komine, Shoichi, Miura, Ikuru, Nagayama, Suminori, Ohmori, Hajime, Nagasaki, Yukio Advanced healthcare materials 10 (10) (2021)
  8. An Antioxidant Nanoparticle Enhances Exercise Performance in Rat High-intensity Running Models Toriumi, Takuto, Kim, Ahram, Komine, Shoichi, Miura, Ikuru, Nagayama, Suminori, Ohmori, Hajime, Nagasaki, Yukio Advanced healthcare materials 10 (10) (2021)
  9. Improving silymarin oral bioavailability using silica-installed redox nanoparticle to suppress inflammatory bowel disease Nguyen, Thu-Ha Thi, Trinh, Nhu-Thuy, Tran, Han Ngoc, Tran, Hao Thi, Le, Phong Quoc, Ngo, Dai-Nghiep, Tran-Van, Hieu, Van Vo, Toi, Vong, Long Binh, Nagasaki, Yukio Journal of controlled release : official journal of the Controlled Release Society 331 515 - 524 (2021)
  10. Newly Developed Self-assembling Antioxidants as Potential Therapeutics for the Cancers Babita, Shashni, 長崎, 幸夫 Journal of Personalized Medicine 11 (92) (2021)
  11. Management of Tumor Growth and Angiogenesis in Triple-Negative Breast Cancer by using Redox Nanoparticles Babita, Shashni, Yuji, Nishikawa, 長崎, 幸夫 Biomaterials 269 120645 (2021)
  12. Newly Developed Self-assembling Antioxidants as Potential Therapeutics for the Cancers Babita, Shashni, 長崎, 幸夫 Journal of Personalized Medicine 11 (92) (2021)
  13. Molecular design of a high-performance polymeric carrier for delivery of a variety of boronic acid-containing drugs Kim, Ahram, Suzuki, Yuya, Nagasaki, Yukio ACTA BIOMATERIALIA 121 554 - 565 (2021)
  14. Molecular design of a high-performance polymeric carrier for delivery of a variety of boronic acid-containing drugs Kim, Ahram, Suzuki, Yuya, Nagasaki, Yukio Acta Biomaterialia 121 554 - 565 (2021)
  15. Improving Silymarin Oral Bioavailability Using Silica-installed Redox Nanoparticle to Suppress Inflammatory Bowel Disease Nguyen, Thu-Ha Thi, Trinh, Nhu-Thuy, Tran, Han Ngoc, Tran, Hao Thi, Le, Phong Quoc, Ngo, Dai-Nghiep, Tran-Van, Hieu, Vo, Toi Van, Vong, Long Binh, Nagasaki, Yukio Journal of Controlled Release 331 515 - 524 (2021)
  16. Management of Tumor Growth and Angiogenesis in Triple-Negative Breast Cancer by using Redox Nanoparticles Babita, Shashni, Yuji, Nishikawa, 長崎, 幸夫 Biomaterials (2021)
  17. Non-isotope enriched phenylboronic acid-decorated dual-functional nano-assembles for an actively targeting BNCT drug Kim, Ahram, Suzuki, Minoru, Matsumoto, Yoshitaka, Fukumitsu, Nobuyoshi, Nagasaki, Yukio Biomaterials 268 120551 - 120551 (2021)
  18. Fibrinolytic Tissue Plasminogen Activator Installed Redox-Active Nanoparticles (t-PA@iRNP) for Cancer Therapy Mei, Ting, Shashni, Babita, Maeda, Hiroshi, Nagasaki, Yukio Biomaterials 259 120290 (2020)
  19. Fibrinolytic tissue plasminogen activator installed redox-active nanoparticles (t-PA@iRNP) for cancer therapy Mei, Ting, Shashni, Babita, Maeda, Hiroshi, Nagasaki, Yukio Biomaterials 259 120290 (2020)
  20. Nitric Oxide Nano-Delivery Systems for Cancer Therapeutics: Advances and Challenges Vong, Long Binh, Nagasaki, Yukio Antioxidants (Basel, Switzerland) 9 (9) (2020)

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※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。

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知財 / Intellectual properties

  1. 特願2022-009170 : ポリ(疎水化システイン)セグメントをブロックとして含む共重合体及びその治療用途 甲田, 優太, 長崎幸夫, シャスニ, バビータ, 斉藤孝輔
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COTRE(コトリ)|COmmunity of Tsukuba REsearchers

発行:筑波大学 URA研究戦略推進室・研究推進部