深水 昭吉 / Fukamizu, Akiyoshi
生存ダイナミクス研究センター 教授 / Professor, Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)
関連記事 / Related Articles in COTRE
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- Deficiency of cardiac natriuretic peptide signaling promotes peripartum cardiomyopathy-like remodeling in the mouse heart
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- Phosphatidylinositol 3-Kinase/Akt Regulates Angiotensin II-Induced Inhibition of Apoptosis in Microvascular Endothelial Cells by Governing Survivin Expression and Suppression of Caspase-3 Activity
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- Guanylyl cyclase-A inhibits angiotensin II type 1A receptor-mediated cardiac remodeling, an endogenous protective mechanism in the heart
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- Benfotiamine counteracts glucose toxicity effects on endothelial progenitor cell differentiation via Akt/FoxO signaling
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- Regulation of PGC-1 promoter activity by protein kinase B and the forkhead transcription factor FKHR
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生命の源「海」を見つめ、 「ヒト」をより深く理解する
海洋生物学リサーチユニット Investigate the source of life “sea” to deeply understand “human beings”
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脂質の量から質へ 生活習慣病治療のパラダイムシフトをめざして
脂質エネルギー代謝リサーチユニット From Quantitative to Qualitative Aspects of Lipids: Toward a Paradigm Shift in the Treatment of Lifestyle-Related Diseases
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- Regulatory roles for APJ, a seven-transmembrane receptor related to angiotensin-type 1 receptor in blood pressure in vivo
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- Silent information regulator 2 potentiates Foxo 1-mediated transcription through its deacetylase activity
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- Mechanical stress activates angiotensin II type 1 receptor without the involvement of angiotensin II
論文 / Publication
- The molecular and neural regulation of ultraviolet light phototaxis and its food-associated learning behavioral plasticity in C. elegans Ozawa, Kazuki, Shinkai, Yoichi, Kako, Koichiro, Fukamizu, Akiyoshi, Doi, Motomichi Neuroscience letters 770 (2021)
- Temporal transcriptomic profiling reveals dynamic changes in gene expression of Xenopus animal cap upon activin treatment Yumeko Satou-Kobayashi, Jun-Dal Kim, Akiyoshi Fukamizu, Makoto Asashima 11 (1) (2021)
- siRNA screening identifies METTL9 as a histidine Nπ-methyltransferase that targets the proinflammatory protein S100A9 Daitoku, Hiroaki, Someya, Momoka, Kako, Koichiro, Hayashi, Takahiro, Tajima, Tatsuya, Haruki, Hikari, Sekiguchi, Naoki, Uetake, Toru, Akimoto, Yuto, Fukamizu, Akiyoshi The Journal of biological chemistry 297 (5) (2021)
- m(6)A-mediated alternative splicing coupled with nonsense-mediated mRNA decay regulates SAM synthetase homeostasis Watabe, Eichi, Togo-Ohno, Marina, Ishigami, Yuma, Wani, Shotaro, Hirota, Keiko, Kimura-Asami, Mariko, Hasan, Sharmin, Takei, Satomi, Fukamizu, Akiyoshi, Suzuki, Yutaka, Suzuki, Tsutomu, Kuroyanagi, Hidehito EMBO JOURNAL 40 (14) (2021)
- ヒスタミンH3アゴニストによる心腎連関病態への抗炎症作用メカニズムの解析 野口 和之, 石田 純治, 金 俊達, 室町 直人, 臼井 丈一, 山縣 邦弘, 深水 昭吉 日本腎臓学会誌 63 (4) 509 - 509 (2021)
- Disruption of entire locus leads to embryonic lethality by diminished gene expression and enhanced p53 pathway Dinh, Tra Thi Huong, Iseki, Hiroyoshi, Mizuno, Seiya, Iijima-Mizuno, Saori, Tanimoto, Yoko, Daitoku, Yoko, Kato, Kanako, Hamada, Yuko, Hasan, Ammar, Shaker Hamed, Suzuki, Hayate, Murata, Kazuya, Muratani, Masafumi, Ema, Masatsugu, Kim, Jun-Dal, Ishida, Junji, Fukamizu, Akiyoshi, Kato, Mitsuyasu, Takahashi, Satoru, Yagami, Ken-Ichi, Wilson, Valerie, Arkell, Ruth M, Sugiyama, Fumihiro eLife 10 (2021)
- Orientation of mouse H19 ICR affects imprinted H19 gene expression through promoter methylation-dependent and -independent mechanisms Matsuzaki, Hitomi, Miyajima, Yu, Fukamizu, Akiyoshi, Tanimoto, Keiji Communications biology 4 (1) 1410 (2021)
- ヒスタミンH3受容体と心臓-腎臓関連マウスモデルにおけるにおける遺伝子発現心臓プロファイリング(Cardiac profiling of gene expression in a mouse model of cardio-renal association with the histamine H3 receptor agonist) 室町 直人, 石田 純治, 野口 和之, 金 俊達, 深水 昭吉 96 (4) 1118 - 1118 (2021)
- Roles of protein arginine methyltransferase 1 (PRMT1) in brain development and disease Hashimoto, Misuzu, Fukamizu, Akiyoshi, Nakagawa, Tsutomu, Kizuka, Yasuhiko Biochimica et biophysica acta. General subjects 1865 (1) 129776 - 129776 (2021)
- Age-dependent decline in remyelination capacity is mediated by apeline-APJ signaling Masumi, Ito, Rieko, Muramastu, Yuki, Kato, Bikram, Sharma, Akiko, Uyeda, Shogo, Tanabe, Haruyoshi, Fujimura, Hiroyaasu, Kidoya, Nobuyuki, Takakura, Yukio, Kawahara, Masaki, Takao, Hideki, Mochizuki, Fukamizu, Akiyoshi, Toshihide, Yamashita Nature Aging 1 (3) 284 - 294 (2021)
- 線虫の新規ヒスチジンメチル化酵素METL-18の自己メチル化と生物学的意義の解析 春木 陽香理, 大徳 浩照, 田島 達也, 加香 孝一郎, 深水 昭吉 日本生化学会大会プログラム・講演要旨集 93回 [1Z09 - 166)] (2020)
- 線虫における新規ヒスチジンメチル化酵素METL-18の機能解析 大徳 浩照, 田島 達也, 春木 陽香理, 染谷 百香, 加香 孝一郎, 深水 昭吉 日本生化学会大会プログラム・講演要旨集 93回 [P - 170] (2020)
- ヒスタミンH3受容体アゴニストの心腎病態での遺伝子発現プロファイリング 室町 直人, 金 俊達, 石田 純治, 野口 和之, 深水 昭吉 日本生化学会大会プログラム・講演要旨集 93回 [3Z10 - 605)] (2020)
- Transcriptomic Evaluation of Pulmonary Fibrosis-Related Genes: Utilization of Transgenic Mice with Modifying p38 Signal in the Lungs Matsuda, Shuichi, Kim, Jun-Dal, Sugiyama, Fumihiro, Matsuo, Yuji, Ishida, Junji, Murata, Kazuya, Nakamura, Kanako, Namiki, Kana, Sudo, Tatsuhiko, Kuwaki, Tomoyuki, Hatano, Masahiko, Tatsumi, Koichiro, Fukamizu, Akiyoshi, Kasuya, Yoshitoshi International journal of molecular sciences 21 (18) 6746 - 6746 (2020)
- Loss of PRMT1 in the CNS induces reactive astrocytes and microglia during postnatal brain development Misuzu Hashimoto, Ayako Kumabe, Jun‐Dal Kim, Kazuya Murata, Sowmya Sekizar, Anna Williams, Weizhe Lu, Junji Ishida, Tsutomu Nakagawa, Mitsuharu Endo, Yasuhiroasuhiro Minami, Akiyoshi Fukamizu (2020)
- Transcriptomic changes involved in the dedifferentiation of myofibroblasts derived from the lung of a patient with idiopathic pulmonary fibrosis Suzuki, Kenichi, Kim, Jun-Dal, Ugai, Keita, Matsuda, Shuichi, Mikami, Hideki, Yoshioka, Kento, Ikari, Jun, Hatano, Masahiko, Fukamizu, Akiyoshi, Tatsumi, Koichiro, Kasuya, Yoshitoshi Molecular medicine reports 22 (2) 1518 - 1526 (2020)
- H3受容体アゴニストの抗炎症作用を介した心腎病態保護作用の解明 野口 和之, 石田 純治, 金 俊達, 室町 直人, 加香 孝一郎, 金子 修三, 臼井 丈一, 山縣 邦弘, 深水 昭吉 日本腎臓学会誌 62 (4) 300 - 300 (2020)
- Identification of a novel nucleolar protein complex required for mitotic chromosome segregation through centromeric accumulation of Aurora B Fujimura, Akiko, Hayashi, Yuki, Kato, Kazashi, Kogure, Yuichiro, Kameyama, Mutsuro, Shimamoto, Haruka, Daitoku, Hiroaki, Fukamizu, Akiyoshi, Hirota, Toru, Kimura, Keiji Nucleic acids research 48 (12) 6583 - 6596 (2020)
- Region-specific upregulation of HNK-1 glycan in the PRMT1-deficient brain Hashimoto, Misuzu, Hirata, Tetsuya, Yonekawa, Chizuko, Takeichi, Kaho, Fukamizu, Akiyoshi, Nakagawa, Tsutomu, Kizuka, Yasuhiko Biochimica et biophysica acta. General subjects 1864 (3) 129509 - 129509 (2020)
- Deficiency of Cardiac Natriuretic Peptide Signaling Promotes Peripartum Cardiomyopathy-Like Remodeling in the Mouse Heart. Otani K, Tokudome T, Kamiya CA, Mao Y, Nishimura H, Hasegawa T, Arai Y, Kaneko M, Shioi G, Ishida J, Fukamizu A, Osaki T, Nagai-Okatani C, Minamino N, Ensho T, Hino J, Murata S, Takegami M, Nishimura K, Kishimoto I, Miyazato M, Harada-Shiba M, Yoshimatsu J, Nakao K, Ikeda T, Kangawa K Circulation 141 (7) 571 - 588 (2020)
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※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。
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知財 / Intellectual properties
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- 特願2014-090001 : 化合物の抗炎症効果または免疫抑制効果を予測する方法 深水昭吉, 金俊逹, 大黒理勝
- 2015-12850 : 細胞を分離・解析する方法 深水昭吉, 金俊達, 萩原昌彦, 和田幸周
- 2015-12851 : 活性化白血球の除去方法 深水昭吉, 金俊達, 萩原昌彦, 和田幸周
- 2014-190001 : 化合物の抗炎症効果または免疫抑制効果を予測する方法 深水昭吉, 金俊達, 大黒, 理勝
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