坂本 透 / Sakamoto, Tohru

医学医療系 准教授 / Associate Professor, Faculty of Medicine

関連記事 / Related Articles in COTRE

Overexpression of GATA-3 protects against the development of hypersensitivity pneumonitis
Exposure to diesel exhaust exacerbates allergen-induced airway responses in guinea pigs
Transcription factors T-bet and GATA-3 regulate development of airway remodeling
Role of 15-deoxyΔ prostaglandin J2 and Nrf2 pathways in protection against acute lung injury
患者さんのゲノム配列をもとに、最適な治療を提供する
ゲノム医科学リサーチユニット
Optimal Treatments Based on Patients’ Genome Sequences
Genome-wide association study identifies three new susceptibility loci for adult asthma in the Japanese population
Genome-wide association study identifies eight new susceptibility loci for atopic dermatitis in the Japanese population
Nrf2 Enhances Cell Proliferation and Resistance to Anticancer Drugs in Human Lung Cancer

 

論文 / Publication

  1. Genetic impact ofCDHR3on the adult onset of asthma and COPD Shigemasa, Rie, Masuko, Hironori, Hyodo, Kentaro, Kitazawa, Haruna, Kanazawa, Jun, Yatagai, Yohei, Iijima, Hiroaki, Naito, Takashi, Saito, Takefumi, Hirota, Tomomitsu, Tamari, Mayumi, Sakamoto, Tohru, Hizawa, Nobuyuki CLINICAL AND EXPERIMENTAL ALLERGY Epub (2020)
  2. Effects of Lung Function-Related Genes and on COPD Phenotypes Yamada, Hideyasu, Hida, Norihito, Masuko, Hironori, Sakamoto, Tohru, Hizawa, Nobuyuki COPD 17 (1) 59 - 64 (2020)
  3. ORMDL3/GSDMB Genotype as a Risk Factor for Early-Onset Adult Asthma Is Linked to Total Serum IgE Levels but Not to Atopy Kitazawa, H, Masuko, H, Shigemasa, R, Hyodo, K, Kanazawa, J, Yamada, H, Yatagai, Y, Iijima, H, Naito, T, Saito, T, Konno, S, Hirota, T, Tamari, M, Sakamoto, T, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 201 (2020)
  4. Genetic Impact of CDHR3 on the Adult Onset of Chronic Inflammatory Airway Diseases Shigemasa, R, Masuko, H, Hyodo, K, Kitazawa, H, Kanazawa, J, Lijima, H, Naito, T, Saito, T, Hirota, T, Tamari, M, Sakamoto, T, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 201 (2020)
  5. Exacerbation Clusters Demonstrate Asthma and Chronic Obstructive Pulmonary Disease Overlap with Distinct Phenotypes Hyodo, K, Masuko, H, Oshima, H, Shigemasa, R, Kitazawa, H, Kanazawa, J, Iijima, H, Kodama, T, Nomura, A, Kagohashi, K, Sato, H, Saito, T, Sakamoto, T, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 201 (2020)
  6. The Concavity of the Maximal Expiratory Flow-Volume Curve Reflects the Extent of Emphysema in Obstructive Lung Diseases Mochizuki, Fumi, Iijima, Hiroaki, Watanabe, Azusa, Tanabe, Naoya, Sato, Susumu, Shiigai, Masanari, Fujiwara, Keiji, Shimada, Takafumi, Ishikawa, Hiroichi, Kanazawa, Jun, Yatagai, Yohei, Masuko, Hironori, Sakamoto, Tohru, Muro, Shigeo, Hizawa, Nobuyuki SCIENTIFIC REPORTS 9 (2019)
  7. Small-Cell Lung Cancer Treatment of Newly Diagnosed Patients with Poor Performance Status Aida, Yuka, Nakazawa, Kensuke, Shiozawa, Toshihiro, Ogawa, Ryoko, Kiwamoto, Takumi, Morishima, Yuko, Sakamoto, Toru, Sekine, Ikuo, Hizawa, Nobuyuki CASE REPORTS IN ONCOLOGY 12 (2) 613 - 620 (2019)
  8. A cis-eQTL allele regulating reduced expression of CHI3L1 is associated with late-onset adult asthma in Japanese cohorts Kanazawa, Jun, Kitazawa, Haruna, Masuko, Hironori, Yatagai, Yohei, Sakamoto, Tohru, Kaneko, Yoshiko, Iijima, Hiroaki, Naito, Takashi, Saito, Takefumi, Noguchi, Emiko, Konno, Satoshi, Nishimura, Masaharu, Hirota, Tomomitsu, Tamari, Mayumi, Hizawa, Nobuyuki BMC medical genetics 20 (1) 58 (2019)
  9. Association analyses of eQTLs of the TYRO3 gene and allergic diseases in Japanese populations Kanazawa, Jun, Masuko, Hironori, Yatagai, Yohei, Sakamoto, Tohru, Yamada, Hideyasu, Kitazawa, Haruna, Iijima, Hiroaki, Naito, Takashi, Saito, Takefumi, Noguchi, Emiko, Hirota, Tomomitsu, Tamari, Mayumi, Hizawa, Nobuyuki Allergology international : official journal of the Japanese Society of Allergology 68 (1) 77 - 81 (2019)
  10. Association analyses of eQTLs of the TYRO3 gene and allergic diseases in Japanese populations Kanazawa, Jun, Masuko, Hironori, Yatagai, Yohei, Sakamoto, Tohru, Yamada, Hideyasu, Kitazawa, Haruna, Iijima, Hiroaki, Naito, Takashi, Saito, Takefumi, Noguchi, Emiko, Hirota, Tomomitsu, Tamari, Mayumi, Hizawa, Nobuyuki Allergology international : official journal of the Japanese Society of Allergology (2019)
  11. Genetic Effects of ORMDL3/GSDMB on Asthma Are Modified by the GSDMC Genotype at Chromosome 8 Kitazawa, H, Masuko, H, Kanazawa, J, Shigemasa, R, Hyodo, K, Yatagai, Y, Iijima, H, Naito, T, Saito, T, Hirota, T, Tamari, M, Sakamoto, T, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 199 (2019)
  12. A cis-eQTL Allele Lowering Gene Expression of CHL3L1 Is Associated with Late-Onset Adult Asthma in Japanese Shigemasa, R, Kanazawa, J, Kitazawa, H, Masuko, H, Hyodo, K, Yatagai, Y, Sakamoto, T, Kaneko, Y, Iijima, H, Naito, T, Saito, T, Noguchi, E, Konno, S, Nishimura, M, Hirota, T, Tamari, M, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 199 (2019)
  13. Transcription Elongation Factor P-TEFb Is Involved in IL-17F Signaling in Airway Smooth Muscle Cells Masayuki Nakajima, Mio Kawaguchi, Masashi Matsuyama, Kyoko Ota, Junichi Fujita, Satoshi Matsukura, Shau-Ku Huang, Yuko Morishima, Yukio Ishii, Hiroaki Satoh, Tohru Sakamoto, Nobuyuki Hizawa 176 (2) 83 - 90 (2018)
  14. 気道平滑筋細胞におけるIL-6,IL-8産生に対するIL-17FとLABAの増強効果 中嶋, 真之, 川口, 未央, 太田, 恭子, 藤田, 純一, 松山, 政史, 松倉, 聡, 塩澤, 利博, 中澤, 健介, 増子, 裕典, 際本, 拓未, 松野, 洋輔, 森島, 祐子, 佐藤, 浩昭, 坂本, 透, 檜澤, 伸之 アレルギー 67 (4・5) 687 - 687 (2018)
  15. TYRO3: A Gene for Allergic Rhinitis? Kanazawa, J, Masuko, H, Yatagai, Y, Yamada, H, Sakamoto, T, Kitazawa, H, Iijima, H, Naito, T, Hirota, T, Tamari, M, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
  16. Abnormality in Flow Volume Loop of Obstructive Index Reflects the Extent of Emphysema and Disease Severity in Obstructive Lung Diseases Mochizuki, F, Iijima, H, Keiji, F, Shimada, T, Watanabe, A, Shiigai, M, Ishikawa, H, Kanazawa, J, Yatagai, Y, Masuko, H, Sakamoto, T, Oguma, T, Sato, S, Muro, S, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
  17. Effect of Steroids and Long-Acting-Beta Agonist on IL-17F Induced IL-6 and IL-8 Expression Nakajima, M, Kawaguchi, M, Matsuyama, M, Yoshida, K, Ota, K, Fujita, J, Matsukura, S, Huang, S, Morishima, Y, Ishii, Y, Satoh, H, Sakamoto, T, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
  18. How Important Is Allergic Sensitization as a Cause of Atopic Asthma? Yatagai, Y, Kanazawa, J, Masuko, H, Yamada, H, Sakamoto, T, Kitazawa, H, Iijima, H, Naito, T, Hirota, T, Tamari, M, Hizawa, N AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE 197 (2018)
  19. Genetic association of the functional CDHR3 genotype with early-onset adult asthma in Japanese populations Jun Kanazawa, Hironori Masuko, Yohei Yatagai, Tohru Sakamoto, Hideyasu Yamada, Yoshiko Kaneko, Haruna Kitazawa, Hiroaki Iijima, Takashi Naito, Takefumi Saito, Emiko Noguchi, Satoshi Konno, Masaharu Nishimura, Tomomitsu Hirota, Mayumi Tamari, Nobuyuki Hizawa 66 (4) 563 - 567 (2017)
  20. 難治性器質化肺炎加療中に気管支鏡検査で肺MALTリンパ腫と診断しえた1例 岡村, 純子, 春日, 真理子, 際本, 拓未, 田地, 広明, 會田, 有香, 中嶋, 真之, 吉田, 和史, 塩澤, 利博, 中澤, 健介, 増子, 裕典, 小川, 良子, 松野, 洋輔, 川口, 未央, 森島, 祐子, 坂本, 透, 石井, 一弘, 坂下, 麻衣, 坂下, 信悟, 野口, 雅之, 檜澤, 伸之 気管支学 39 (3) 288 (2017)

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発行:筑波大学 URA研究戦略推進室・研究推進部