柳沢 裕美 / Yanagisawa, Hiromi

生存ダイナミクス研究センター 教授 / Professor, Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance (TARA)

関連記事 / Related Articles in COTRE

ラマン分光法における大動脈瘤の診断マーカースペクトルを同定
血管障害後の新生内膜形成に関わる細胞の役割を解明
細胞外環境から生命現象を捉える | 柳沢 裕美 | 筑波大学研究者カタログ
TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis
Disturbed flow promotes arterial stiffening through thrombospondin-1
大動脈瘤発症の分子機構解明と新しい治療標的分子の探索
慢性腎臓病に対する新規治療法の開発にむけた基礎研究
皮膚が老化すると「幹細胞の顔」が変わる! ~加齢に伴う皮膚幹細胞の糖鎖変化の解析に成功~
細胞外マトリクスを介した新しいメカノトランスダクション機構を発見 〜血管疾患への新たな治療法開発への期待〜
#027:血管の異常を引き起こすシグナルを探して 細胞と細胞外環境とをシームレスに捉える
血管の異常を引き起こすシグナルを探して 細胞と細胞外環境とをシームレスに捉える
大動脈瘤形成に関与するメカノトランスダクション機構を解明 〜新しい治療標的分子の特定〜
大動脈瘤形成に関与するシグナル伝達経路を解明 〜大動脈瘤治療の新たな標的分子として期待〜

 

論文 / Publication

  1. Raman microspectroscopy and Raman imaging reveal biomarkers specific for thoracic aortic aneurysms Kaori Sugiyama, Julia Marzi, Julia Alber, Eva M. Brauchle, Masahiro Ando, Yoshito Yamashiro, Bhama Ramkhelawon, Katja Schenke-Layland, Hiromi Yanagisawa 100261 (2021)
  2. Contribution of PDGFRα-positive cells in maintenance and injury responses in mouse large vessels. Kenichi Kimura, Karina Ramirez, Tram Anh Vu Nguyen, Yoshito Yamashiro, Aiko Sada, Hiromi Yanagisawa 11 (1) 8683 - 8683 (2021)
  3. Dysregulated assembly of elastic fibers in fibulin-5 knockout mice results in a tendon-specific increase in elastic modulus Jeremy D. Eekhoff, Heiko Steenbock, Ian M. Berke, Jürgen Brinckmann, Hiromi Yanagisawa, Jessica E. Wagenseil, Spencer P. Lake 113 104134 - 104134 (2021)
  4. Defining compartmentalized stem cell populations with distinct cell division dynamics in the ocular surface epithelium Ishii, Ryutaro, Yanagisawa, Hiromi, Sada, Aiko Development (Cambridge, England) 147 (24) (2020)
  5. The molecular mechanism of mechanotransduction in vascular homeostasis and disease Yamashiro, Yoshito, Yanagisawa, Hiromi Clinical science (London, England : 1979) 134 (17) 2399 - 2418 (2020)
  6. Glycome profiling by lectin microarray reveals dynamic glycan alterations during epidermal stem cell aging Oinam, Lalhaba, Changarathil, Gopakumar, Raja, Erna, Ngo, Yen Xuan, Tateno, Hiroaki, Sada, Aiko, Yanagisawa, Hiromi Aging cell 19 (8) (2020)
  7. Role of PAR1-Egr1 in the Initiation of Thoracic Aortic Aneurysm in Fbln4-Deficient Mice Shin, Seung Jae, Hang, Huynh Thuy, Thang, Bui Quoc, Shimoda, Tomonari, Sakamoto, Hiroaki, Osaka, Motoo, Hiramatsu, Yuji, Yamashiro, Yoshito, Yanagisawa, Hiromi Arteriosclerosis, thrombosis, and vascular biology ATVBAHA120314560 (2020)
  8. TBX1 Regulates Chondrocyte Maturation in the Spheno-occipital Synchondrosis. N Funato, D Srivastava, S Shibata, H Yanagisawa Epub 22034520925080 - 22034520925080 (2020)
  9. Matrix mechanotransduction mediated by thrombospondin-1/integrin/YAP in the vascular remodeling. Yoshito Yamashiro, Bui Quoc Thang, Karina Ramirez, Seung Jae Shin, Tomohiro Kohata, Shigeaki Ohata, Tram Anh Vu Nguyen, Sumio Ohtsuki, Kazuaki Nagayama, Hiromi Yanagisawa 117 (18) 9896 - 9905 (2020)
  10. Novel ELN mutation in a Japanese family with a severe form of supravalvular aortic stenosis. Kaori Sugiyama, Hitoshi Horigome, Lisheng Lin, Takashi Murakami, Junko Shiono, Yoshito Yamashiro, Hiroyuki Matsuura, Hitoshi Yoda, Hiromi Yanagisawa 7 (11) e986 (2019)
  11. Fibulin-4 exerts a dual role in LTBP-4L-mediated matrix assembly and function. Heena Kumra, Valentin Nelea, Hana Hakami, Amelie Pagliuzza, Jelena Djokic, Jiongci Xu, Hiromi Yanagisawa, Dieter P Reinhardt 116 (41) 20428 - 20437 (2019)
  12. Recent updates on the molecular network of elastic fiber formation Shin, Seung Jae, Yanagisawa, Hiromi Essays in biochemistry (2019)
  13. 大動脈形成に関与するメカノトランスダクション機構 山城 義人, 柳沢 裕美 医学のあゆみ 269 (7) 552 - 553 (2019)
  14. Wild-type and SAMP8 mice show age-dependent changes in distinct stem cell compartments of the interfollicular epidermis Changarathil, G, Karina, R, Isoda, H, Sada, A, Yanagisawa, H PLoS One 14 (5) e0215908 (2019)
  15. 左単一冠動脈の拡張を伴い、SHOC2遺伝子異常が認められたNoonan症候群の1例 石川, 伸行, 堀米, 仁志, 村上, 卓, 高橋, 実穂, 野崎, 良寛, 林, 立申, 塩野, 淳子, 平松, 祐司, 柳沢, 裕美 日本小児循環器学会雑誌 = Acta cardiologica paediatrica Japonica 35 (2) 127 - 131 (2019)
  16. Fibulin-4 deficiency differentially affects cytoskeleton structure and dynamics as well as TGFβ signaling Burger, Joyce, van Vliet, Nicole, van Heijningen, Paula, Kumra, Heena, Kremers, Gert-Jan, Alves, Maria, van Cappellen, Gert, Yanagisawa, Hiromi, Reinhardt, Dieter, Kanaar, Roland, van der Pluijm, Ingrid, Essers, Jeroen Cellular signalling 58 65 - 78 (2019)
  17. Elastic fibers and biomechanics of the aorta: Insights from mouse studies Yanagisawa, Hiromi, Wagenseil, Jessica Matrix biology : journal of the International Society for Matrix Biology Epub (2019)
  18. Fibulin-7, a heparin binding matricellular protein, promotes renal tubular calcification in mice. Jun Tsunezumi, Hidekazu Sugiura, Lalhaba Oinam, Aktar Ali, Bui Quoc Thang, Aiko Sada, Yoshito Yamashiro, Makoto Kuro-O, Hiromi Yanagisawa 74 5 - 20 (2018)
  19. Role of Thrombospondin-1 in Mechanotransduction and Development of Thoracic Aortic Aneurysm in Mouse and Humans. Yoshito Yamashiro, Bui Quoc Thang, Seung Jae Shin, Caroline Antunes Lino, Tomoyuki Nakamura, Jungsil Kim, Kaori Sugiyama, Chiho Tokunaga, Hiroaki Sakamoto, Motoo Osaka, Elaine C Davis, Jessica E Wagenseil, Yuji Hiramatsu, Hiromi Yanagisawa 123 (6) 660 - 672 (2018)
  20. Deletion of the T-box transcription factor gene, Tbx1, in mice induces differential expression of genes associated with cleft palate in humans Funato, Noriko, Yanagisawa, Hiromi Archives of oral biology 95 149 - 155 (2018)

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