金保 安則 / Kanaho, Yasunori

筑波大学 理事 / Executive Director, University of Tsukuba

関連記事 / Related Articles in COTRE

Phosphatidylinositol-4-phosphate-5-kinase α deficiency alters dynamics of glucose-stimulated insulin release to improve glucohomeostasis and decrease obesity in mice
腫瘍血管新生における低分子量G蛋白質Arf6の生理機能の解明 ~Arf6シグナル伝達系を標的とした新たな抗癌剤の開発に繋がる可能性~
地中海食薬の研究と創薬で、産業化と雇用創出を目指す
国際食薬・リサーチユニット
Aiming at industrialization and job creation by research and drug discovery of Mediterranean medicinal plants and food medicines
シグナル伝達の異常に起因した疾患 を治療する創薬開発に向けた研究
シグナル伝達と疾患リサーチユニット
Research for drug discovery to treat diseases caused by abnormal cellular signaling
脂質の量から質へ 生活習慣病治療のパラダイムシフトをめざして
脂質エネルギー代謝リサーチユニット
From Quantitative to Qualitative Aspects of Lipids: Toward a Paradigm Shift in the Treatment of Lifestyle-Related Diseases
Sequential regulation of DOCK2 dynamics by two phospholipids during neutrophil chemotaxis
Phosphatidylinositol 4-phosphate 5-kinase α is a downstream effector of the small G protein ARF6 in membrane ruffle formation

 

論文 / Publication

  1. Arf6 regulates energy metabolism in neutrophils Gamara, Jouda, Davis, Lynn, Leong, Andrew Z, Page, Nathalie, Rollet-Labelle, Emmanuelle, Zhao, Chenqi, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Aoudji, Fawzi, Pelletier, Martin, Bourgoin, Sylvain G FREE RADICAL BIOLOGY AND MEDICINE 172 550 - 561 (2021)
  2. Arf6 exacerbates allergic asthma through cell-to-cell transmission of ASC inflammasomes Lee, SangJoon, Ishitsuka, Akari, Kuroki, Takahiro, Lin, Yu-Hsien, Shibuya, Akira, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Nagata, Kyosuke, Kawaguchi, Atsushi JCI INSIGHT 6 (16) (2021)
  3. Arf1 and Arf6 Synergistically Maintain Survival of T Cells during Activation Sumiyoshi, Mami, Kotani, Yui, Ikuta, Yuki, Suzue, Kazutomo, Ozawa, Madoka, Katakai, Tomoya, Yamada, Taketo, Abe, Takaya, Bando, Kana, Koyasu, Shigeo, Kanaho, Yasunori, Watanabe, Toshio, Matsuda, Satoshi JOURNAL OF IMMUNOLOGY 206 (2) 366 - 375 (2021)
  4. TBC1D24 regulates recycling of clathrin-independent cargo proteins mediated by tubular recycling endosomes Nguyen, Thi Kim Nguyen, Ohbayashi, Norihiko, Kanaho, Yasunori, Funakoshi, Yuji BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 528 (1) 220 - 226 (2020)
  5. Inhibitory effect of black raspberry extract on AGE accumulation and degradation, and ROS production in HUVEC cells Dan, Katsuaki, Takada, Atsushi, Kanaho, Yasunori, Kusumi, Yuko, Banno, Harutaka FUNCTIONAL FOODS IN HEALTH AND DISEASE 10 (6) 242 - 253 (2020)
  6. Assessment of Arf6 Deletion in PLB-985 Differentiated in Neutrophil-Like Cells and in Mouse Neutrophils: Impact on Adhesion and Migration Gamara, Jouda, Davis, Lynn, Rollet-Labelle, Emmanuelle, Hongu, Tsunaki, Funakoshi, Yuji, Kanaho, Yasunori, Aoudjit, Fawzi, Bourgoin, Sylvain G Mediators of inflammation 2020 1 - 13 (2020)
  7. Explant Culture of the Embryonic Mouse Spinal Cord and Gene Transfer by ex vivo Electroporation Kinoshita-Kawada, Mariko, Hasegawa, Hiroshi, Hongu, Tsunaki, Yanagi, Shigeru, Kanaho, Yasunori, Masai, Ichiro, Mishima, Takayasu, Chen, Xiaoping, Tsuboi, Yoshio, Rao, Yi, Yuasa-Kawada, Junichi, Wu, Jane Y BIO-PROTOCOL 9 (18) (2019)
  8. A crucial role for Arf6 in the response of commissural axons to Slit Kinoshita-Kawada, Mariko, Hasegawa, Hiroshi, Hongu, Tsunaki, Yanagi, Shigeru, Kanaho, Yasunori, Masai, Ichiro, Mishima, Takayasu, Chen, Xiaoping, Tsuboi, Yoshio, Rao, Yi, Yuasa-Kawada, Junichi, Wu, Jane Y Development (Cambridge, England) 146 (3) (2019)
  9. Physiological function of phospholipase D2 in anti-tumor immunity: Regulation of CD8+ T lymphocyte proliferation Van Ngo Thai Bich, Tsunaki Hongu, Yuki Miura, Naohiro Katagiri, Norihiko Ohbayashi, Yumi Yamashita-Kanemaru, Akira Shibuya, Yuji Funakoshi, Yasunori Kanaho 8 (1) 6283 (2018)
  10. LPA signaling mediates tumor lymphangiogenesis through promoting CRT expression in prostate cancer Lin, Yueh-Chien, Chen, Chien-Chin, Chen, Wei-Min, Lu, Kuan-Ying, Shen, Tang-Long, Jou, Yeong-Chin, Shen, Cheng-Huang, Ohbayashi, Norihiko, Kanaho, Yasunori, Huang, Yuan-Li, Lee, Hsinyu Biochimica et biophysica acta 1863 (10) 1305 - 1315 (2018)
  11. Phospholipase D2 promotes disease progression of renal cell carcinoma through the induction of angiogenin Shuya Kandori, Takahiro Kojima, Taeko Matsuoka, Takayuki Yoshino, Aiko Sugiyama, Eijiro Nakamura, Toru Shimazui, Yuji Funakoshi, Yasunori Kanaho, Hiroyuki Nishiyama 109 (6) 1865 - 1875 (2018)
  12. Oxidized LDL phagocytosis during foam cell formation in atherosclerotic plaques relies on a PLD2–CD36 functional interdependence Ganesan, Ramya, Henkels, Karen M, Wrenshall, Lucile E, Kanaho, Yasunori, Paolo, Gilbert Di, Frohman, Michael A, Gomez‐Cambronero, Julian Journal of Leukocyte Biology 103 (5) 867 - 883 (2018)
  13. Anti-aging effects of black raspberry extract on cataract, alopecia, skin whitening, and weight loss Dan, Katsuaki, Takada, Atsushi, Kanaho, Yasunori, Kusumi, Yuko, Banno, Harutaka FUNCTIONAL FOODS IN HEALTH AND DISEASE 8 (1) 17 - 34 (2018)
  14. ACAP3, the GTPase-activating protein specific to the small GTPase Arf6, regulates neuronal migration in the developing cerebral cortex Miura, Yuki, Kanaho, Yasunori Biochemical and biophysical research communications 493 (2) 1089 - 1094 (2017)
  15. Arf6 in lymphatic endothelial cells regulates lymphangiogenesis by controlling directional cell migration Yueh-Chien Lin, Norihiko Ohbayashi, Tsunaki Hongu, Naohiro Katagiri, Yuji Funakoshi, Hsinyu Lee, Yasunori Kanaho 7 (1) (2017)
  16. Rab32 subfamily small GTPases: Pleiotropic Rabs in endosomal trafficking Norihiko Ohbayashi, Mitsunori Fukuda, Yasunori Kanaho 162 (2) 65 - 71 (2017)
  17. Regulation of HGF-induced hepatocyte proliferation by the small GTPase Arf6 through the PIP2-producing enzyme PIP5K1A Meng-Tsz Tsai, Naohiro Katagiri, Norihiko Ohbayashi, Kenichi Iwasaki, Nobuhiro Ohkohchi, Shih-Torng Ding, Yasunori Kanaho, Yuji Funakoshi 7 (1) 9438 (2017)
  18. The small G protein Arf6 expressed in keratinocytes by HGF stimulation is a regulator for skin wound healing Yuki Miura, Van Ngo Thai Bich, Momoko Furuya, Hiroshi Hasegawa, Satoru Takahashi, Naohiro Katagiri, Tsunaki Hongu, Yuji Funakoshi, Norihiko Ohbayashi, Yasunori Kanaho 7 (2017)
  19. Machineries regulating the activity of the small GTPase Arf6 in cancer cells are potential targets for developing innovative anti-cancer drugs Yamauchi, Yohei, Miura, Yuki, Kanaho, Yasunori Advances in biological regulation 63 115 - 121 (2017)
  20. ACAP3 regulates neurite outgrowth through its GAP activity specific to Arf6 in mouse hippocampal neurons Yuki Miura, Tsunaki Hongu, Yohei Yamauchi, Yuji Funakoshi, Naohiro Katagiri, Norihiko Ohbayashi, Yasunori Kanaho 473 (17) 2591 - 2602 (2016)

researchmap の論文リストを表示する Show the publication list on researchmap

※上記の論文リストは researchmapから取得した論文リストにDOIリンク等の情報を付加したものです。筑波大学研究者総覧(TRIOS)または researchmapの論文リストが更新されると後日反映されます。

論文のオープンアクセス版を読む Check out a freely downloadable version

知財 / Intellectual properties

  1. 特願2010-050431 : Arf6遺伝子機能喪失動物及びその利用方法 金保,安則
  2. 特願2010-063109 : GTP結合型ARF6タンパク質の測定方法及びその用途 金保安則, 本宮綱記, 周淼, 長谷川潤
  3. 特願2010-050431 : Arf6遺伝子機能喪失動物及びその利用方法 金保安則, 本宮綱記, 長谷川潤, 船越祐司
  4. 特願2004-292123 : アレルギーマウス 金保, 安則
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発行:筑波大学 URA研究戦略推進室・研究推進部