Andrea Corsinotti

Andrea Corsinotti (国際テニュアトラック助教)

Andreas Corsinotti

氏名

Name

Andrea Corsinotti

所属

Affiliation

医学医療系

Faculty of Medicine

メンター

Mentor

高橋 智 教授

Professor Satoru Takahashi

派遣先

Host Institution

MRC Centre for Regenerative Medicine, Institute for Stem Cell Research, School of Biological Sciences, University of Edinburgh

Mentor

Professor Ian Chambers

Key wards:Pluripotent states, Embryonic stem cells, Transcription factors, Heterogeneity, CRISPR/Cas9

専門:Genetic approaches for the understanding of pluripotent state transitions in embryonic stem cells and during development.

 

研究概要/Summary

My research interests focus on the understanding of how pluripotency is maintained in mouse embryonic stem cells and how the transitions between pluripotent states are regulated during early development. I am particularly interested in the regulation of key pluripotency transcription factors such as Oct4, Nanog and Sox2. To achieve these aims I am using the CRISPR/Cas9 technology to develop pluripotent cell lines in which the genes encoding for these transcription factors or their regulatory sequences have been engineered.

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